Does Homeostatic Pressure Explain Tumor Growth?
نویسندگان
چکیده
منابع مشابه
Homeostatic competition drives tumor growth and metastasis nucleation.
We propose a mechanism for tumor growth emphasizing the role of homeostatic regulation and tissue stability. We show that competition between surface and bulk effects leads to the existence of a critical size that must be overcome by metastases to reach macroscopic sizes. This property can qualitatively explain the observed size distributions of metastases, while size-independent growth rates c...
متن کاملDoes Erythropoietin Promote Tumor Growth?
In Response: We appreciate Yoon and colleagues’ interest in our report and welcome the opportunity to reply to their comments. Our study was designed in a context in which several clinical trials, including patients with head and neck squamous cell carcinomas, breast cancer, non–small cell lung cancer and nonmyeloid malignancies, showed a potential deleterious effect of recombinant human erythr...
متن کاملDoes a cell protein explain Covid-19 severity
Does a protein on the surface of some of our cells explain why certain people are more at risk from covid-19? The coronavirus attaches to a receptor protein on the surface(ACE) of our cells to gain entry to them. The protein is carried by cells in the nose, lungs and gut. It is possible that variation in how much of this protein people have may help explain why some are more likely to die from ...
متن کاملDoes Classical Competition Explain the Statistical Features of Firm Growth ?
We express the idea of classical competition in a statistical equilibrium model, where the tendency for competition to equalize profit rates results in an exponential power (or Subbotin) distribution. The model supports and extends recent evidence on the Laplace distribution of growth rates in firm size. We also find tent-shaped distributions in the size growth rates of Forbes Global 2000 compa...
متن کاملDoes the European Marriage Pattern Explain Economic Growth?
This paper scrutinizes the recently postulated link between the European Marriage Pattern (EMP) and economic success. A metastudy of the historical demography literature shows that the EMP did not prevail throughout Europe, its three key components did not always coincide, and its more extreme manifestations were associated with economic stagnation rather than growth. There is no evidence that ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2009
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djp193